In the life sciences, there is an ongoing discussion about a perceived ‘reproducibility crisis’. However, it remains unclear to which extent the perceived lack of reproducibility is the consequence of issues that can be tackled and to which extent it may be the consequence of unrealistic expectations of the technical level of reproducibility. Large-scale, multi-institutional experimental replication studies are very cost- and time-intensive. This Perspective suggests an alternative, complementary approach: meta-research using sociological and philosophical methodologies to examine researcher trust in (...) data. An improved understanding of the criteria used by researchers to judge data reliability will provide crucial, initial evidence on the actual scale of the reproducibility crisis and on measures to tackle it. (shrink)

Priest and others have presented their “most telling” argument for paraconsistent logic: that only paraconsistent logics allow non-trivial inconsistent theories. This is a very prevalent argument; occurring as it does in the work of many relevant and more generally paraconsistent logicians. However this argument can be shown to be unsuccessful. There is a crucial ambiguity in the notion of non-triviality. Disambiguated the most telling reason for paraconsistent logics is either question-begging or mistaken. This highlights an important confusion about the role (...) of logic in our development of our theories of the world. Does logic chart good reasoning or our commitments? We also consider another abductive argument for paraconsistent logics which also is shown to fail. (shrink)

Classical logic is explosive in the face of contradiction, yet we find ourselves using inconsistent theories. Mark Colyvan, one of the prominent advocates of the indispensability argument for realism about mathematical objects, suggests that such use can be garnered to develop an argument for commitment to inconsistent objects and, because of that, a paraconsistent underlying logic. I argue to the contrary that it is open to a classical logician to make distinctions, also needed by the paraconsistent logician, which allow a (...) more nuanced ranking of theories in which inconsistent theories can have different degrees of usefulness and productivity. Facing inconsistency does not force us to adopt an underlying paraconsistent logic. Moreover we will see that the argument to best explanation deployed by Colyvan in this context is unsuccessful. I suggest that Quinean approach which Colyvan champions will not lead to the revolutionary doctrines Colyvan endorses. (shrink)

Quine’s general approach is to treat ontology as a matter of what a theory says there is. This turns ontology into a question of which existential statements are consequences of that theory. This approach is contrasted favourably with the view that takes ontological commitment as a relation to things. However within the broadly Quinean approach we can distinguish different accounts, differing as to the nature of the consequence relation best suited for determining those consequences. It is suggested that Quine’s own (...) narrowly formal account fails. Then a consideration of the necessitation approach championed by Jackson and Lewis shows that it does not do justice to the role of acknowledging consequences in determining rationality. I suggest that an approach which puts a priori consequence as the key relation does a better job. The task of spelling out the nature of a priori consequence is sketched, along with reasons to doubt the adequacy of the double indexing approach to analysing the a priori. The sorts of relations we can stand in to theories which allow us to inherit ontological commitments are touched on with a number of important philosophical strategies for introducing belief-like attitudes which nevertheless avoid ontological commitment. (shrink)

In Tichy's influential attack, a number of egregious errors are attributed to Kripke's seminal distinction of epistemic and metaphysical dimensions in meaning. I argue that Tichy's work is based on important misunderstandings. In particular Tichy attributes to Kripke the mistaken view that it is propositions, that is sets of worlds, which are the proper object of the appellation "a priori" and "a posteriori". I show that this is a mistaken attribution. Further, I argue that propositions cannot be uniquely associated with (...) these appellations. Thus, the position Tichy mistakenly attributes to Kripke, a position which Tichy actually endorses, is unsustainable. (shrink)

Inspired by two-dimensional modal logic, some have sought to provide analyses of the notion of the contingent a priori which identify the a priori with truths which have a necessary diagonal. I argue that these analyses fail insofar as they miss the crucial epistemic aspect of the a priori. Augmenting these analyses with specifically epistemic accounts might be possible, but the interest would then reside in these epistemic accounts of the a priori and not in the formal models.

Changes in the methodology of the historical sciences make them more vulnerable to unjustifiable speculations being passed off as scientific results. The integrity of historical science is in peril due the way speculative and often unexamined causal assumptions are being used to generate data and underpin the identification of correlations in such data. A step toward a solution is to distinguish between plausible and speculative assumptions that facilitate the inference from measured and observed data to causal claims. One way to (...) do that is by comparing these assumptions against a well-attested set of aspects of causation, such as the so-called “Bradford Hill Criteria”. The BHC do not provide a test for causation or necessary and sufficient conditions for causation but do indicate grounds for further investigation. By revising the BHC to reflect the needs and focus of historical sciences, it will be possible to assess the cogency of methods of investigation. These will be the Historical Sciences Bradford Hill Criteria. An application to one area in historical science is used to demonstrate the effectiveness of the HSBHC, namely biogeography. Four methods are assessed in order to show how the HSBHC can be used to examine the assumptions between our data and the causal biogeographical processes we infer. (shrink)

Famously, David Lewis argued that we can avoid the apparent paradoxes of time travel by introducing a notion of personal time, which by and large follows the causal flow of the time traveler's life history. This paper argues that a related approach can be adapted for use by three-dimensionalists in response to Ted Sider's claim that three-dimensionalism is inconsistent with time travel. In contrast to Lewis (and others who follow him on this point), however, this paper argues that the order (...) of events captured by so-called "personal time" should be thought of as causal, rather than temporal. (shrink)

We investigate the formal theory of binary quantifiers, that is, quantifiers that take seriously the surface structure of natural language quantifier phrases. We show how to develop a natural deduction system for logics of this sort and demonstrate soundness and completeness results.

(1996). Compatibilist semantics in metaphysics: A case study. Australasian Journal of Philosophy: Vol. 74, No. 1, pp. 117-134. doi: 10.1080/00048409612347101.

Floridi’s Theory of Strongly Semantic Information posits the Veridicality Thesis. One motivation is that it can serve as a foundation for information-based epistemology being an alternative to the tripartite theory of knowledge. However, the Veridicality thesis is false, if ‘information’ is to play an explanatory role in human cognition. Another motivation is avoiding the so-called Bar-Hillel/Carnap paradox. But this paradox only seems paradoxical, if ‘information’ and ‘informativeness’ are synonymous, logic is a theory of inference, or validity suffices for rational inference; (...) a, b, and c are false. (shrink)

Introduction: Philosophy in Mind / Michaelis Michael and John O’Leary-Hawthorne -- AI and the Synthetic A Priori / Jose Benardete -- Armchair Metaphysics /Frank Jackson -- Doubts About Conceptual Analysis /Gilbert Harman -- Deflationary Self-Knowledge / Andre Gallois -- How to Get to Know One’s Own Mind: Some Simple Ways / Annette Baier -- Psychology in Perspective / Huw Price -- Can Philosophy of Language Provide the Key to the Foundations of Ethics? /Karl-Otto Apel --Unprincipled Decisions / Lee (...) Overton -- Philosophy and Commonsense: The Case of Weakness of Will / Jeanette Kennett and Michael Smith -- Reasoning and Representing / Robert Brandom -- The Problem of Consciousness / John Searle -- Godel’s Theorem and the Mind... Again / Graham Priest -- Epistemology and the Diet Revolution / Gilbert Harman -- Truth-Aptness and Belief / John O’Leary-Hawthorne -- Cubism, Perspective, Belief / Michaelis Michael. Objectivity and Modern Idealism: What is The Question? / Gideon Rosen. (shrink)

David Lewis presented a celebrated argument for the identity theory of mind. His argument has provided the model for the program of analytic functionalism. He argues from two premises, that mental states are analytically tied to their causal roles and that, contingently, there is never a need to explain any physical change by going outside the realm of the physical, to the conclusion that mental states are physical. I show that his argument is mistaken and that it trades on a (...) crucial ambiguity in the second premise. He argues for a weaker version of that premise and then uses a stronger version in the argument. The weaker version of that premise will not allow the inference and the stronger version is contested in the dialectical context. In general then this strategy for providing analytic reductions will not be guaranteed to succeed. (shrink)

Is the theory of evolution by means of natural selection a tautology? This book explores the explanatory structure of Darwin’s theory at a time when selectionist explanations are being brought forward to explain a wider and wider range of phenomena.

ABSTRACTLloyd encourages us to look anew at philosophy and science by using a comparative methodology, comparing the familiar Western form of philosophy, for example, with the forms found in ancient China. Taking lessons from comparative biology, this paper attempts to show that such comparison can only take place when we understand what we are looking at in the familiar case. The question of the centrality of the drive for certainty is addressed. Why has certainty been so attractive and what does (...) it mean if philosophers and scientists cannot achieve certainty? (shrink)

Do our lives have meaning? Should we create more people? Is death bad? Should we commit suicide? Would it be better if we were immortal? Should we be optimistic or pessimistic? Life, Death, and Meaning brings together key readings, primarily by English-speaking philosophers, on such 'big questions.'.

Do our lives have meaning? Should we create more people? Is death bad? Should we commit suicide? Would it be better to be immortal? Should we be optimistic or pessimistic? Since Life, Death, and Meaning: Key Philosophical Readings on the Big Questions first appeared, David Benatar's distinctive anthology designed to introduce students to the key existential questions of philosophy has won a devoted following among users in a variety of upper-level and even introductory courses.

Pancreatitis is a complex, progressively destructive inflammatory disorder. Alcohol was long thought to be the primary causative agent, but genetic contributions have been of interest since the discovery that rare PRSS1, CFTR and SPINK1 variants were associated with pancreatitis risk. We now report two associations at genome-wide significance identified and replicated at PRSS1-PRSS2 and X-linked CLDN2 through a two-stage genome-wide study. The PRSS1 variant likely affects disease susceptibility by altering expression of the primary trypsinogen gene. The CLDN2 risk allele is (...) associated with atypical localization of claudin-2 in pancreatic acinar cells. The homozygous CLDN2 genotype confers the greatest risk, and its alleles interact with alcohol consumption to amplify risk. These results could partially explain the high frequency of alcohol-related pancreatitis in men. © 2012 Nature America, Inc. All rights reserved. (shrink)

Notre temps est, dit-on, celui des catastrophes. Sur les nouveaux fronts de l’écologie, du changement climatique ou de la menace nucléaire, les idéologies du progrès ont cédé la place à l’angoisse. Mais la résurgence des thèmes apocalyptiques est bien plus que le symptôme d’une période de crise : dès les XVIe et XVIIe siècles, avec la disparition du cosmos comme ordre hiérarchisé au sein duquel l’homme occupait une position privilégiée, est née une nouvelle inquiétude : celle de devoir vivre « (...) après la fin du monde ». Ce livre voudrait montrer que le plus urgent n’est pas d’éviter la catastrophe à venir, mais de repenser et de réinvestir le monde de manière nouvelle. Michaël Foessel interprète les peurs apocalyptiques actuelles à partir des expériences contemporaines où les sujets se sentent dépossédés du monde : triomphe de la technique sur l’action, du capital sur le travail, du besoin sur le désir. Pour cela, il propose une généalogie de l’idée de « fin du monde » qui distingue deux voies de la modernité : celle qui privilégie la vie et sa conservation, aujourd’hui à l’oeuvre dans la plupart des conceptions écologiques et précautionneuses du réel ; celle qui fait du monde le thème principal de la philosophie en même temps qu’un enjeu politique de premier ordre. Nous sommes désormais face à une alternative : perpétuer la vie ou édifier un monde. Les théories de la catastrophe ne se soucient plus de savoir quel monde mérite d’être défendu. En ce sens, le fait que la fin du monde a déjà eu lieu est une bonne nouvelle : cela nous invite à inventer des espaces pour l’action et à fonder un nouveau cosmopolitisme. (shrink)

" L'énigme, c'est précisément qu'il semble évident que le monde existe pour nous. " C'est à cette énigme que se confronte Kant dès ses premiers écrits. Le projet critique de Kant prend son origine dans la critique de la cosmologie classique. A chaque étape de son développement, des écrits pré-critiques à l'Opus postumum, le rapport au monde est spécifié, que ce soit du point de vue de la sensibilité, de la connaissance ou de la morale. Avec Kant s'ouvre un nouvel (...) horizon pour l'homme, comme " habitant du monde ". Le monde moral et surtout le concept de liberté dont l'origine est cosmologique prennent une nouvelle dimension et se substituent à un hypothétique " monde intelligible ". C'est l'occasion pour Michaël Foessel de revisiter la " maison Kant " dans ses coins et recoins, de mettre à l'épreuve la rationalité de l'édifice, dans une confrontation féconde entre Kant, Husserl et Heidegger. Une lecture forte et vivifiante. (shrink)

En 1789, la Révolution française met la liberté à l'ordre du jour. C'est un événement pour la philosophie qui, au siècle des Lumières, a activement participé à la critique du despotisme. C'est aussi un événement philosophique qui délivre à la pensée de nouveaux horizons où les maîtres-mots sont souveraineté politique du peuple et autonomie morale du sujet. De Rousseau, qui fait de la liberté le fondement de toute légitimité, à Hegel pour qui "l'esprit est liberté", en passant par Kant qui (...) consacre le droit inaliénable des peuples à disposer d'eux-mêmes, Michaël Foessel revient sur cette période philosophique si intense. Au cours de ces bouleversements historiques s'élabore une définition de la liberté irréductible au libéralisme. C'est parce que notre époque est incertaine sur le sens de la liberté qu'il vaut la peine d'entendre à nouveau l'exigence d'autonomie portée par la philosophie, de Rousseau à Hegel. (shrink)

v. 1. Opuscula logica, physica, allegorica, alia -- v. 2. Opuscula psychologica, theologica, daemonologica.

This book offers a new account of the origins of modern biblical criticism. Focusing on the scholarship of J. D. Michaelis , it shows how critics created a post-theological academic Bible to replace Europe's scriptural Bibles and assimilate biblical scholarship to the social goals of the Enlightenment.

Commentaries on Aristotle's writings have been produced since the 2nd century AD. This edition contains Greek commentaries on his work from the 3rd to the 8th centuries AD by, among others, Alexander of Aphrodiensias, Themistios, Joh. Philoponus, Simplicius in Greek.

Seit dem 2. nachchristlichen Jahrhundert werden die Schriften von Aristoteles kommentiert. Diese Ausgabe enthält griechische Kommentare zu seinem Werk vom 3. bis 8. Jahrhundert n. Chr., u. a. von Alexander von Aphrodiensias, Themistios, Joh. Philoponus, Simplicius in griechischer Sprache.

Michael Walzer zahlt zu den bedeutendsten politischen Theoretikern der Gegenwart. Gleichwohl weist die weltweite Aufmerksamkeit einen `blinden` Fleck auf, wenn es darum geht, Walzers kommunitaristische Gerechtigkeitsphilosophie vor dem Hintergrund der judischen politischen Theorie zu situieren. Diese Lucke will der Sammelband schliessen, indem erstmals im deutschsprachigen Raum die vielschichtigen Interdependenzen zwischen Religion und Politik in Walzers Werk unter dem Stichwort der Politischen Theologie systematisch interpretiert werden. Mit Beitragen von:Edmund Arens, Thomas Bedorf, Micha Brumlik, Martin Hartmann, Michael Haus, Otto Kallscheuer, (...) Joachim J. Krause, Skadi Krause, Michael Kuhnlein, Jurgen Manemann, John Milbank, Peter Nitschke, Henning Ottmann, Rolf Schieder, Christoph Seibert, Michael Walzer, Jean-Pierre Wils und einer Replik von Michael Walzer. (shrink)

Die hiermit herausgegebene Briefsammlung des Bischofs von Athen Michael Choniates ist unter zweierlei Aspekten besonders wichtig: Einerseits wegen der Information, die uns über die Zustände im byzantinischen Reich im allgemeinen und in Athen und Umgebung bzw. auf einigen Inseln der Ägäis insbesondere sowie über die Gesellschaft jener Zeit (Ende des 12. – Anfang des 13. Jahrhunderts) bietet, andererseits wegen der Briefe selbst, die nicht nur die starke Orientierung der zeitgenössischen Gelehrten auf die Literatur des alten Hellas verraten, sondern auch (...) unter den anmutigsten und stilistisch interessantesten, die je in byzantinischer Zeit abgefaßt wurden, zählen. (shrink)

PurposeScarce evidence exists regarding end-of-life decision (EOLD) in neurocritically ill patients. We investigated the factors associated with EOLD making, including the group and individual characteristics of involved healthcare professionals, in a multiprofessional neurointensive care unit (NICU) setting.Materials and methodsA prospective, observational pilot study was conducted between 2013 and 2014 in a 10-bed NICU. Factors associated with EOLD in long-term neurocritically ill patients were evaluated using an anonymised survey based on a standardised questionnaire.Results8 (25%) physicians and 24 (75%) nurses participated in (...) the study by providing their ‘treatment decisions’ for 14 patients at several time points. EOLD was ‘made’ 44 (31%) times, while maintenance of life support 98 (69%) times. EOLD patterns were not significantly different between professional groups. The individual characteristics of the professionals (age, gender, religion, personal experience with death of family member and NICU experience) had no significant impact on decisions to forgo or maintain life-sustaining therapy. EOLD was patient-specific (intraclass correlation coefficient: 0.861), with the presence of acute life-threatening disease (OR (95% CI): 18.199 (1.721 to 192.405), p=0.038) and low expected patient quality of life (OR (95% CI): 9.276 (1.131 to 76.099), p=0.016) being significant and independent determinants for withholding or withdrawing life-sustaining treatment.ConclusionsOur findings suggest that EOLD in NICU relies mainly on patient prognosis and not on the characteristics of the healthcare professionals. (shrink)

According to the received account of guilt in the philosophical literature, one cannot feel guilt unless one takes oneself to have done something morally wrong. But ordinary people feel guilt in many cases in which they do not take themselves to have done anything morally wrong. In this paper, I focus on one kind of guilt without perceived wrongdoing, guilt about being merely causally responsible for a bad state-of-affairs. I go on to present a novel account of guilt that explains (...) guilt about mere causal responsibility, according to which guilt represents part of the self as bound up with what is bad. (shrink)